Media Encoder mistakenly encodes MP4 as VR - BUG
When encoding a ProRes QT to an H264 MP4, AME will sometimes incorrectly interpret the file as VR, which completely messes it up.
For some reason, the resulting file looks distorted when viewed with some apps (eg: VLC and PotPlayer on Win10), but it looks normal in others (eg: when viewed on Dropbox.com)
The fix is seemingly to check and uncheck "Video is VR" under the Video export settings. I'm not sure if anyone else has encountered this issue?

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Stanislao Cantono di Ceva commented
YES!! It's very annoying! It automatically encodes VR if the ratio is exactly 2:1, which is the format commonly used by 360 pano VR.
F.e. if you try a 1920x960 px ratio, which is the standard late 90's UNIVISIUM ratio, it will result in a useless VR file...
PLEASE ADOBE PROVIDE A WORKAROUND!!! -
Galen Fott commented
Terrible problem, I'm sending videos to clients that they can't use because of this. I have checked to make sure "video is VR" is turned off (I don't know how it got turned on to begin with), but it STILL encodes as VR sometimes. Happens with 16:9 and other aspects as well, doesn't seem to matter. I'm using AME 22.3 on a Mac.
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Kalleheikki Kannisto commented
Same here. This just started recently. Both H264 and H265 high quality automatically turn on "video is VR" when I drag a video to be converted into the Encoder. I trashed Media Encoder preferences to no avail. Now I need to turn it off manually on every conversion.
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Michael Douglas commented
@Tom G - sorry it's happening to you too.
FYI, sometimes AME automatically turns the "Video is VR" button by itself, but other times it encodes as VR without it being checked, and then I have to check and uncheck it so I get the correct result. Generally it has only been messing this up with non 16:9 renders, but now it's doing it for some of those too. Yay.
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Tom G commented
Same over here with AME 15.02 and AE 18.02 in Windows 10.
BUT it only seems to happen on formats that are not in a 16:9 ratio.