Keyframe pinning options in Effect Controls Panel: pin to IN and/or OUT point(s)
PROBLEM:
Every time an editor trims the in point of a clip that has keyframes at/near the in point, those keyframes lose their positioning relationship to the clip's in point: trim inwards and keyframes are trimmed out of view in the ECP, trim outwards and the keyframes no longer apply to the beginning of the clip as intended. The same problem applies when trimming a clip's out point with keyframes at/near the out point.
SOLUTION:
Keyframe pinning checkboxes in the ECP would allow keyframes to move together in unison with a clip's in and/or out points when trimming a clip in the Timeline. (see illustration)
In point checked: with the In point checkbox checked, all keyframes would move along with the clip's in point when trimming.
Out point checked: with the Out point checkbox checked, all keyframes would move along with the clip's out point when trimming.
In+Out point checked: with both checkboxes checked, only the keyframes in the first half of the clip would move when trimming the clip's in point. Likewise, only the keyframes in the second half of the clip would move when trimming the out point. NOTE 1: Users would be allowed to trim a clip up to the point that any two keyframes collide. For example, if there are 2 Scale keyframes 30 frames apart near the center of the clip, one in the first half and the other in the second half, the user would only be allowed to trim the clip's in or out point inward up to 29 frames since at that point the two keyframes would be bumped up against each other. NOTE 2: checking one or both checkboxes could also serve as a method of preventing keyframes from moving when slipping a clip. This could effectively replace the need for the following FR in which I suggest using a Keyboard modifier to control whether or not keyframes move with the clip when slipping: https://adobe-video.uservoice.com/forums/911233-premiere-pro/suggestions/38075233-slip-clip-keyboard-modifier-that-would-make-a-hug
Neither checked: with neither checkbox checked, keyframes would behave the way they currently do: staying put when trimming, or moving when slipping the clip.
FINAL NOTES: The checkboxes should be 'sticky', meaning that when a user switches clips in the ECP, closes and reopens a project, or even creates a new project, the last used checkbox setting should remain. Since users would probably want their keyframes to stick most of the time, it would probably be best to have these 2 checkboxes checked by default when first using Pr.
As always, thanks for listening!

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Jonno Woodford-Robinson commented
ALSO, if we could pan the keyframe part of the window beyond the clip to the first or last keyframe, this would be good, too. Sometimes we want the timing/acceleration of the action to remain the same but want to start from a higher or lower position. Allowing access to the keyframe even when it's out of view (by dragging the screen left and right with a Hand tool), that would also improve user experience.
Thanks!
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Andreas Lukas commented
I very often use subtle zoom/pan effects in clips. But during edit the clips are trimmed several times. Always adjusting the keyfromes to start and end of the clip is aweful timekiller.
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Andreas Lukas commented
That would be such a great feature and simple to implement!
Please have a look at this post: https://adobe-video.uservoice.com/forums/911233-premiere-pro/suggestions/41647414-responsive-keyframes-ability-to-stick-keyframes
I think this could also solve your problem!?
If you like it please also vote for it. Thanks!!
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Pierre Louis Beranek commented
Hi Adobe, I know this isn't one of those flashy feature requests that will get a lot of attention, but having keyframes move every time a clip is slipped is an absolute time killer, especially when trying to slip a clip with speed keyframes. I suggest you do a test to try it out: add 2 or more time remap keyframes to a clip. Now try to slip that clip by a few frames while keeping the keyframes in sync with the clip's in/out points as well as everything else in the Timeline. Frustrated yet? The fact users can't move more than one time remapping keyframe at once only exacerbates this problem!
PLEASE fix this! Thank you kindly!